Hydroxypinorésinol
Aller à la navigation
Aller à la recherche
Nom de la substance
Hydroxypinorésinol
Famille moléculaire
Source végétale
Propriétés
- Neuroprotecteur (9-hydroxypinorésinol) [2]
- Antioxydant [3], [4]
- Activité vasorelaxante (8-hydroxypinorésinol) [5]
- Ligand pour les récepteurs aux benzodiazépines [6]
Effet thérapeutique
Effets indésirables
Bibliographie
- ↑ Wang PC, Ran XH, Chen R, Luo HR, Ma QY, Liu YQ, Hu JM, Huang SZ, Jiang HZ, Chen ZQ, Zhou J, Zhao YX. Sesquiterpenoids and lignans from the roots of Valeriana officinalis L. Chem Biodivers. 2011 Oct;8(10):1908-13. doi: 10.1002/cbdv.201000247. PMID 22006719
- ↑ Cui HS, Sok DE, Min BS, Kim MR. Protective action of 9-hydroxypinoresinol against oxidative damage in brain of mice challenged with kainic acid. J Pharm Pharmacol. 2007 Apr;59(4):521-8. Erratum in J Pharm Pharmacol. 2007 Nov;59(11):1585. PMID 17430635
- ↑ Salido S, Pérez-Bonilla M, Adams RP, Altarejos J. Phenolic Components and Antioxidant Activity of Wood Extracts from 10 Main Spanish Olive Cultivars. J Agric Food Chem. 2015 Jul 29;63(29):6493-500. doi: 10.1021/acs.jafc.5b02979. PMID 26154988
- ↑ Xue J, Mi Y, Wang Z, Sun Y, Wu Q, Wang C, Zhang H, Yang X, Kuang H, Wang Q. Determination and pharmacokinetic study of four lignans in rat plasma after oral administration of an extract of Valeriana amurensis by ultra-high performance liquid chromatography with tandem mass spectrometry. J Sep Sci. 2016 May;39(10):1825-33. doi: 10.1002/jssc.201600038. PMID 26991028
- ↑ Piccinelli AL, Arana S, Caceres A, di Villa Bianca Rd, Sorrentino R, Rastrelli L. New lignans from the roots of Valeriana prionophylla with antioxidative and vasorelaxant activities. J Nat Prod. 2004 Jul;67(7):1135-40.
- ↑ Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol. 1999 May;51(5):505-12. PMID 10411208